Archives for the ‘Cool Science’ Category

Gordon the robot has a biological brain made of rat neurons

Scientists have created the first rat cyborg.

Every time the robot nears an object, signals are directed to stimulate the brain by means of the electrodes, the researchers explained in a statement released today by the University of Reading in England. In response, the brain’s output drives the robot’s wheels left and right, so that it moves around in an attempt to avoid hitting objects.

The robot has no additional control from a human or a computer, the scientists state. Its sole means of control is from its own brain.

“This new research is tremendously exciting as firstly the biological brain controls its own moving robot body, and secondly it will enable us to investigate how the brain learns and memorizes its experiences,” said the university’s Kevin Warwick of the School of Systems Engineering. “This research will move our understanding forward of how brains work, and could have a profound effect on many areas of science and medicine.”

Factor in Moore’s Law. I am envisioning ratbots providing airport security screening as one possible application. Only a few years away. TSA cyborgs with a prediliction towards stealing your cheese will decide whether or not you get to travel. No worries, they’ll have a badge to make it all seem more normal to you.

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The artificial pancreas is coming

Transhumanist technologies are going to explode in the next two to three decades. We already have a crude artificial heart on the market. Now it appears that an artificial pancreas is just around the corner.

Today, people with diabetes have a range of technologies to help keep their blood sugar in check, including continuous monitors that can keep tabs on glucose levels throughout the day and insulin pumps that can deliver the drug. But the diabetic is still responsible for making executive decisions–when to test his blood or give himself a shot–and the system has plenty of room for human error. Now, however, researchers say that the first generations of an artificial pancreas, which would be able to make most dosing decisions without the wearer’s intervention, could be available within the next few years.

Type 1 diabetes develops when the islet cells of the human pancreas stop producing adequate amounts of insulin, leaving the body unable to regulate blood-sugar levels on its own. Left unchecked, glucose fluctuations over the long term can lead to nerve damage, blindness, stroke and heart attacks. Even among the most vigilant diabetics, large dips and surges in glucose levels are still common occurrences. “We have data on hand today that suggests that you could get much better diabetes outcomes with the computer taking the lead instead of the person with diabetes doing it all themselves,” says Aaron Kowalski, research director of the Juvenile Diabetes Research Foundation’s Artificial Pancreas Project.

The artificial pancreas project is good news for diabetics. However, barriers to implementation remain.

Technologically, the remaining obstacles for researchers are those of refinement–for example, constructing algorithms that are exquisitely honed to predict in which direction glucose levels are moving and at what rate. Other researchers are working on sensors that can monitor blood glucose over an extended period of time (currently, sensors must be replaced every three to eight days) and with improved accuracy.

Despite the fact that much of the technology is on the market, researchers must still prove to the FDA that their system is safe when combined with the algorithms, and that if anything goes wrong–if a sensor goes wonky or the insulin pump clogs up–the computer can sense it and either set off an alarm or turn the whole system off.

I’m irritated anytime the FDA is mentioned in a news article. Personally, it’s not clear to me that this organization has helped more people than it hurts. FDA rules slow down the medical technology development process and make it much more expensive. If I ever become a chronically ill patient, I’ll goddamn well seek the medical treatment I want regardless of FDA rules. If I have to leave the United States to get a particular treatment, so be it. I own my own life.

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Exercise and healthy eating habits lead to increased intelligence

Most people are at least dimly aware that regular exercise generally produces health benefits. But not everyone knows that those benefits extend beyond the body and into the human brain.

The bottom line: Exercisers learn faster, remember more, think clearer and bounce back more easily from brain injuries such as a stroke. They are also less prone to depression and age-related cognitive decline.

But why should a mindless half-hour on a treadmill affect your brain?

Exercise, like hunger, is a stress on your body. “And sometimes,” said Fernando Gomez-Pinilla of UCLA, “stress can be good.”

Exercise alone, however, isn’t the complete prescription for an extended and healthful life.

“Diet, exercise and sleep have the potential to alter our brain health and mental function,” he said. “This raises the exciting possibility that changes in diet are a viable strategy for enhancing cognitive abilities, protecting the brain from damage, and counteracting the effects of aging.”

Gómez-Pinilla analyzed more than 160 studies about food’s affect on the brain, an analysis published in the July issue of the journal Nature Reviews Neuroscience.

If you’re wondering why it is so hard to get off the couch and get outdoors, maybe it’s that bag of Cheetos you’ve been masticating for the last hour. Try skipping those next time you sit down to watch Paris Hilton acting retarded in reruns of The Simple Life.

Calorie restriction

Controlled meal skipping or intermittent caloric restriction might provide health benefits, he said.

Excess calories can reduce the flexibility of synapses and increase the vulnerability of cells to damage by causing the formation of free-radicals. Moderate caloric restriction could protect the brain by reducing oxidative damage to cellular proteins, lipids and nucleic acids, Gómez-Pinilla said.

The brain is highly susceptible to oxidative damage. Blueberries have been shown to have strong antioxidant capacity, he noted. And smaller food portions with the appropriate nutrients seem to be beneficial for the brain’s molecules, he said.

Junk food, junk brain

In contrast to the healthy effects of diets that are rich in omega-3 fatty acids, diets with high contents of trans fats and saturated fats adversely affect cognition, studies indicate.

“Junk food” and fast food negatively affect the brain’s synapses, said Gómez-Pinilla, who eats fast food less often since conducting this research.

Brain synapses and several molecules related to learning and memory are adversely affected by unhealthy diets, said Gómez-Pinilla.

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Five things you must know about sleep

Having trouble sleeping? Here’s some advice.

This is the classic not-so-shut-eye experience of many Americans who think they are sleep-deprived and possibly need pills or other treatment to fix their insomnia, teeth grinding, jet lag, restless or jerky legs, snoring, sleepwalking and so forth.

Reality is quite different.

For instance, insomnia is said to be the most common sleep disorder, but these dissatisfying sleep experiences only get in the way of daily activities for 10 percent of us, according to the National Institutes of Health. And in almost half of those cases, the real underlying problem is illness (often mental) or the effects of a substance, like coffee or medication.

The most interesting thing in the article was the concept of polyphasic sleep.

So-called polyphasic sleep is seen in babies, the elderly and other animals (and Thomas Edison reportedly slept this way). For the rest of us, it is more realistic and healthy to sleep at night as best we can and then take naps as needed. EEGs show that we are biphasic sleepers with two alertness dips - one at night time and one mid-day. So talk to HR about setting up a nap room, like they have for NASA’s Phoenix mission team members.

The rest of the advice was kind of mixed. If I tried to get away with a “mid day desk nap” I probably wouldn’t be working at my current job for much longer.

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Aging is a disease that can be cured

At least that’s what Aubrey de Grey believes. I want to believe it as well. I am not interested in dying at this time. Transhumanists may not be in the media spotlight now, but it’s likely the future will change that.

…James Hughes, an administrator and instructor at Trinity College in Hartford, is a leading transhumanist theorist. The executive director of the Institute for Ethics and Emerging Technologies, which he co-founded when he was the executive director of the World Transhumanist Association, Hughes has written several books on transhumanist ideas, including Citizen Cyborg: Why Democratic Societies Must Respond to the Redesigned Human of the Future.

It would appear that Hughes, a buttoned-down professor-type with a close-cropped goatee, is dealing with ideas better suited to science fiction than the real world. However, he traces transhumanist history back to old, earth-bound traditions.

“It goes back to the enlightenment, about 400 years or so,” Hughes said. “And when you go back to those original ideas, you see a number of things emerging, among them the notion that science and tech can be applied to human affairs, and things can be engineered and improved upon.”

While the average earth dweller of 2008 may feel uncomfortable with the idea of engineering a human being they will still pay for LASIK surgery or a hip replacement. If they could safely and cheaply replace the human heart with a model that wasn’t prone to spasms we call heart attacks that often lead to death, most people would get the replacement put in without much serious consideration. In the next two decades, we should see a massive increase in the number and type of life extending, life quality enhancing surgeries available. This is assuming we can avoid universal health care, which will cause stagnation, in my opinion. I am unaware of pioneering surgeries recently developed in France or Britain. I could be wrong, but it seems to me that government socialized health care is statist in nature.

There is no reason not to expect to live 150-200 years if you are 20 today and in good health. Assuming you’re not a partner in a meth lab, wearing a soldier’s uniform or engaged in extreme sports, you have a shot at living a very, very long time in comparison to people born 50 years ago. Depending on social upheaval and battles over the world natural resources you might live to see the middle or the end of the millenium.

Many people are not interested in this idea, particularly those who have not yet faced death and found it to be a distinctly unpalatable notion. For those among you who do not believe in one or another of the various death cults of the world, I highly recommend keeping an eye on the activities of the Methuselah Foundation.

Stem cell research is just the beginning of the end of aging.

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